Publications

Muscedere JG, Martin CM and Heyland DK.  The Impact of Ventilator-Associated Pneumonia on the Canadian Health Care System.  Journal of Critical Care 2008; 23(1):5-10.  Full Text pdf  (with permission from Elsevier) 

Delisle M, Williamson DR, Perreault MM, et al.  The Clinical Significance of Candida Colonization of Respiratory Tract Secretions in Critically Ill Patients.  Journal of Critical Care 2008;23(1):11-17.  Full Text pdf  (with permission from Elsevier)

Parker CM, Kutsogiannis J, Muscedere J, et al.  Ventilator-Associated Pneumonia Caused by Multidrug-Resistant Organisms or Pseudomonas aeruginosa:  Prevalence, Incidence, Risk Factors, and Outcomes.  Journal of Critical Care 2008;23(1):18-26.  Full Text pdf  (with permission from Elsevier)

Muscedere JG, McColl C, Shorr A, et al.  Determinants of Outcome in Patients With a Clinical Suspicion of Ventilator-Associated Pneumonia.  Journal of Critical Care 2008;23(1):41-49.  Full Text pdf  (with permission from Elsevier)

Lauzier F, Ruest A, Cook D, et al.  The Value of Pretest Probability and Modified Clinical Pulmonary Infection Score to Diagnose Ventilator-Associated Pneumonia.  Journal of Critical Care 2008;23(1):50-57.  Full Text pdf  (with permission from Elsevier)

Sanders KM, Adhikari KJ, Friedrich JO, et al.  Previous Cultures Are Not Clinically Useful for Guiding Empiric Antibiotics in Suspected Ventilator-Associated Pneumonia:  Secondary Analysis From a Randomized Trial.  Journal of Critical Care 2008;23(1):58-63.  Full Text pdf  (with permission from Elsevier)

Shorr AF, Cook D, Jiang X, et al.  Correlates of Clinical Failure in Ventilator-Associated Pneumonia:  Insights From a Large, Randomized Trial.  Journal of Critical Care 2008;23(1):64-73.  Full Text pdf  (with permission from Elsevier)

Albert M, Friedrich JO, Adhikari, et al.  Utility of Gram Stain in the Clinical Management of Suspected Ventilator-Associated Pneumonia:  Secondary Analysis of a Multicenter Randomized Trial.  Journal of Critical Care 2008;23(1):74-81.  Full Text pdf  (with permission from Elsevier)

Joffe AR, Muscedere J, Marshall JC, et al.  The Safety of Targeted Antibiotic Therapy for Ventilator-Associated Pneumonia:  A Multicenter Observational Study.  Journal of Critical Care 2008;23(1):82-90.  Full Text pdf  (with permission from Elsevier)

Sinuff T, Muscedere J, Cook D, et al.  Ventilator-Associated Pneumonia:  Improving Clinical Outcomes Through Guideline Implementation.  Journal of Critical Care 2008;23(1): 118-125.  Full Text pdf  (with permission from Elsevier)

Muscedere J, Dodek P, Keenan S, et al.  Comprehensive Evidence-Based Clinical Practice Guidelines for Ventilator-Associated Pneumonia:  Prevention. Journal of Critical Care 2008;23(1):126-137.  Full Text pdf  (with permission from Elsevier)

Muscedere J, Dodek P, Keenan S, et al.  Comprehensive Evidence-Based Clinical Practice Guidelines for Ventilator-Associated Pneumonia:  Diagnosis and Treatment.  Journal of Critical Care 2008;23(1):138-147.  Full Text pdf  (with permission from Elsevier)

The Canadian Critical Care Trials Group. A Randomized Trial of Diagnostic Techniques for Ventilator-Associated Pneumonia. N Engl J Med 2006; 355: 2619-30 Full Text pdf 

Muscedere JG, Heyland DK, Dodek P, Cook DJ for the Canadian Critical Care Trials Group. A Randomized Trial of Invasive Diagnostic Techniques and Empiric Broad-Spectrum Antibiotics for Suspected Ventilator-Associated Pneumonia. Proceedings of the American Thoracic Society, 2006 3:A525 Abstract

Seguin P, Tanguy M, Laviolle B, Tirel O, Malledant Y. Effect of oropharyngeal decontamination by povidone-iodine on ventilator-associated pneumonia in patients with head trauma. Crit Care Med. 2006 May 34(5):1514-9 Pubmed Abstract 

Boots RJ, George N, Faoagali JL, Druery J, Dean K, Heller RF. Double-heater-wire circuits and heat-and-moisture exchangers and the risk of ventilator-associated pneumonia. Crit Care Med. 2006 Mar 34(3):687-93 Pubmed Abstract 

Kollef M, Pittet D, Sanchez Garcia M, Chastre J et al. Prevention of Pneumonia Study (POPS-1) Trial Group. A randomized double-blind trial of iseganan in prevention of ventilator-associated pneumonia. Am J Respir Crit Care Med. 2006 Jan 1;173(1):91-7 Pubmed Abstract 

Dodek P, S. Keenan S , Cook DJ, Heyland DK et al. Evidence Based Clinical Based Guideline for the Prevention of Ventilator Associated Pneumonia. Ann Intern Med. 2004 141:305-313 Pubmed Abstract  

Heyland DK, Cook DJ, Dodek P. Prevention of ventilator-associated pneumonia (VAP): A survey of Canadian practice. J Critical Care 2002 17:161-167 Pubmed Abstract 

Heyland DK, Cook DJ, Heule M, Marshall J, Guslits B, Lang J, Jaeschke R. The clinical utility of invasive diagnostic techniques in the setting of ventilator-associated pneumonia. Chest 1999 115:1076-1084 Pubmed Abstract 

 
    VAP Clinical Practice Guidelines Published


    Lessons Learned from the Canadian VAP Study